Transcranial Magnetic Stimulation (TMS) for Complex Regional Pain Syndrome (CRPS)
Stanford University
Summary
The aim of the current study is to assess the efficacy of TMS in the treatment of Complex Regional Pain Syndrome (CRPS). It is hypothesized that participants who receive TMS (Group 1) relative to sham treatment (Group 2) once daily for two days will demonstrate a greater improvement in CRPS-related pain and other associated symptomology (i.e., cognitive, emotional and physical) compared to baseline. Participants will be followed until they reach their baseline for two consecutive weeks to assess safety and duration of symptom alleviation.
Eligibility
- Age range
- 18–70 years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * Age 18-70 * Diagnosis of CRPS (complex regional pain syndrome) for at least 3 months * Average pain level reported on Numerical Rating Scale meets entry criteria * Ability to perform the experimental task and procedures. Exclusion Criteria: * MRI contraindication (metal implants or devices, claustrophobia) * TMS Contraindication (eg metal implant or devices near the site of stimulation) * History of epilepsy * History of a psychological or psychiatric disorder that would interfere with study procedures, at the discretion of the researcher. * Neurologic illness that wou…
Interventions
- DeviceTranscranial Magnetic Stimulation (TMS)
The Magventure TMS stimulator will be used to perform intermittent theta burst followed by high frequency Transcranial Magnetic Stimulation (TMS).
Location
- Stanford Pain Management CenterRedwood City, California