Functional Assessment in Liver Transplant Candidates (FrAILT) Study
University of California, San Francisco
Summary
This will be a prospective cohort study of patients with liver disease. Subjects will undergo geriatric assessments of frailty, functional status, and disability using functional status measures at baseline and at every clinic visit in the pre-transplant setting. Subjects will also answer questions regarding quality of life, personality, and/or cognitive function. Subjects will again undergo assessments at every clinic visit through 12 months after transplant. Then, they will be followed annually.
Description
Patients will be asked to perform the following study procedures: 1. Assessment of cognitive function, quality of life, and/or personality using cognitive tests and questionnaires. 2. Measures of frailty and disability selected to capture the multi-dimensional aspects of frailty including functional status and physiologic reserve: Fried Frailty Score: weakness (test of grip strength), exhaustion (patient interview), slowness (gait speed), low activity (patient interview) Short Physical Performance Battery: repeated chair stands, balance testing with feet together, 13-foot walk 3. Laborato…
Eligibility
- Age range
- 18+ years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * Adult (≥18 years old) * Are seen for the treatment of liver disease
Locations (12)
- University of Arkansas for Medical SciencesLittle Rock, Arkansas
- Loma Linda UniversityLoma Linda, California
- University of California, San FranciscoSan Francisco, California
- Northwestern UniversityChicago, Illinois
- Indiana UniversityIndianapolis, Indiana
- Johns HopkinsBaltimore, Maryland