Evaluating the Efficacy of Platelet-rich Plasma Therapy in the Treatment of Androgenic Alopecia
Wake Forest University Health Sciences
Summary
The study team will assess the efficacy of platelet-rich plasma therapy, a special blood product which is from the participant's own body, in the treatment of androgenic alopecia (also known as male pattern hair loss) in females.
Description
Androgenic alopecia, or male-pattern hair loss affects both men and women. This hair loss pattern is typically characterized by thinning at the crown of scalp and/or M-shaped hair line in males or diffuse thinning throughout in females. Platelet-rich plasma (PRP) therapy has recently been studied as a hair rejuvenation therapy in patients with non-inflammatory alopecia. Though the mechanism of action is not well understood, PRP is thought to promote angiogenesis and enhance blood flow around hair follicles via platelet-derived growth factor (PDGF), transforming growth factor (TGF), and vascula…
Eligibility
- Age range
- 18+ years
- Sex
- Female
- Healthy volunteers
- No
Inclusion Criteria: * Female ≥18 years of age at baseline visit. * Documentation of androgenic alopecia diagnosis as evidenced by one or more clinical features * Not currently on any treatment for alopecia, or has undergone 2-week washout period if recently on medication(s) for alopecia * Written informed consent obtained from subject and ability for subject to comply with the requirements of the study Exclusion Criteria: * Pregnant or breastfeeding * Presence of a condition or abnormality that in the opinion of the Investigator would compromise the safety of the patient or the quality of t…
Interventions
- BiologicalPlatelet-rich Plasma Left Side
Group A will receive PRP on left side of scalp and placebo (saline solution) on right side of scalp.
- BiologicalPlatelet-rich Plasma Right Side
Group B will receive PRP on right side of scalp and placebo (saline solution) on left side of scalp.
Location
- Wake Forest University Baptist HealthWinston-Salem, North Carolina