Pharmacokinetics of Drugs Administered to Children Per Standard of Care
Duke University
Summary
This is a prospective study of children \<21 years of age with the goal of characterizing the PK of drugs administered per standard of care as prescribed by the treating caregiver.
Eligibility
- Age range
- 0–20 years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * Children (\< 21 years of age) who are receiving understudied drugs of interest per standard of care as prescribed by their treating caregiver Exclusion Criteria: * Failure to obtain consent/assent (as indicated)
Interventions
- DrugStandard of care drug
This study is collecting PK data on children prescribed the following drugs of interest per standard of care: dexmedetomidine, bosentan, furosemide, chlorothiazide, ethacrynic acid, bumetanide, hydromorphone, tacrolimus, ampicillin, gentamicin, caffeine, fentanyl, midazolam, foscarnet, hydroxychloroquine, and moxifloxacin.
Location
- Duke UniversityDurham, North Carolina