Incidence of Neurocognitive Deficits in Patients After Treatment for Retinoblastoma With Multiple Anesthesia Exposures

Summary

The purpose of this study is to see if there is a difference between the development of the brain (neurodevelopment) in children who have been treated for retinoblastoma with multiple anesthetic exposures, compared with brain development in children who have never had anesthesia.

Eligibility

Age range

6–17 years

Sex

All

Healthy volunteers

No

Interventions

• Other
  Wechsler Intelligence Scale for Children, Fifth Edition (WISC-V)

  the WISC-V assessment produces a Full Scale IQ (FSIQ) used for primary power consideration in this study. The FSIQ is the most comprehensive global ability score on the WISC-V, and it has been conventionally reported and interpreted as an estimation of overall intellectual ability

• Other
  California Verbal Learning Test, Children's Version

  Used to assess verbal learning and memory in children and adolescents

• Other
  Beery Developmental Test of Visual Motor Integration, 6th edition

  Helps assess visual-motor skills in children and adults.

• Other
  Grooved Pegboard Test

  Measures dexterity

• Other
  Behavior Assessment System for Children/Parent Report

  The Behavior Assessment System for Children/Parent Report is a questionnaire that assesses the social-emotional and behavioral functioning (e.g., anxiety, depression, attention, hyperactivity, adaptability, leadership, social skills, etc.) in children between the ages of 2 and 22 years, and is available in English and Spanish.

Location