Children's Hospital Medical Center, Cincinnati
The investigators are wanting to learn more about early development of the lungs and to help them better understand prematurity and the development of a breathing disorder call BPD (Bronchopulmonary Dysplasia)
This is an observational case study involving up to three MRI visits. The first MRI will be complete after the infant's clinical initial evaluation. The second image will be obtained approximately 1 month later and the third MRI will be complete prior to discharge. Infants will be imaged at various ages, based up their initial evaluation. The investigators will collect urine and obtain clinically collected remnant blood around time of MRI, tracheal/endotracheal aspirate at time of the MRI when available and BAL samples as clinically available. MRI findings will be correlated with laboratory fi…
Inclusion Criteria: * any term age NICU patient Exclusion Criteria: * \- ECMO, * Evidence of congenital diseases that may affect lung development, such as congenital diaphragmatic hernia, * Suspected muscular dystrophy or neurologic disorder that may affect lung development. * Significant genetic or chromosomal abnormalities that may affect lung development * Evidence of any respiratory infection at the time of imaging (imaging may be rescheduled for a common viral infection such as a cold). * Standard MRI exclusion criteria as set forth by the CCHMC Department of Radiology. This includes a…
MRI device that is not FDA approved.
Polysomnography to better determine obstruction index in the airway.
Arctuva estimate
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