Johns Hopkins University
In this project, the investigators will investigate the effects of a selective serotonin reuptake inhibitor (SSRI), escitalopram, on augmenting language therapy effectiveness, as measured by naming untrained pictures and describing pictures, in individuals with aphasia in the acute and subacute post stroke period (i.e., within three months post stroke).
In this project, the investigators will investigate the effects of a selective serotonin reuptake inhibitor (SSRI), escitalopram, on augmenting language therapy effectiveness, as measured by naming untrained pictures and describing pictures, in individuals with aphasia in the acute and subacute post stroke period (i.e., within three months post stroke). There has been no previous randomized controlled trial (RCT) to evaluate the effect of daily SSRI in the first three months after stroke on improvement of language in people undergoing aphasia treatment. It is plausible that SSRIs, which elevat…
Inclusion Criteria: * Participants must have sustained an acute ischemic left hemisphere stroke. * Participants must be fluent speakers of English by self-report. * Participants must be capable of giving informed consent or indicating a legally authorized representative to provide informed consent. * Participants must be age 18 or older. * Participants must be within 5 days of onset of stroke. * Participants must be pre-morbidly right-handed by self-report. * Participants must have an aphasia diagnosis as confirmed by the Western Aphasia Battery-Revised (Aphasia Quotient \< 93.8). Exclusion…
Escitalopram tablet
Sugar pill manufactured to mimic escitalopram 10 mg tablet
15 45-minute sessions of computer-delivered naming treatment beginning two months following stroke
Arctuva estimate
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