Single Institution (UNM) Prospective Laboratory Study of Cancer and Immune Cells in the Ascites Fluid of Ovarian Cancer Patients to Test Alternative Therapies
New Mexico Cancer Research Alliance
Summary
Ascites samples from women undergoing surgery for ovarian cancer will be collected for use in translational research.
Description
The purpose of this study is to collect ascites fluid obtained from ovarian cancer patients during cytoreductive surgery or paracentesis at the University of New Mexico Hospital or Cancer Center. Cancer cells and immune cells from the ascites fluid will be used to test novel immunotherapies for ovarian cancer treatment and to establish patient derived xenograft models to perform preclinical testing on a cancer cell population that better models the heterogeneity in patient disease
Eligibility
- Age range
- 18+ years
- Sex
- Female
- Healthy volunteers
- Not specified
Inclusion Criteria: * All female participants, regardless of ethnicity, who are undergoing cytoreductive surgery for ovarian cancer are eligible for this study * All participants will be eighteen years old or older * Patients must be suspected of having a pathological diagnosis or clinical suspicion of ovarian cancer and be scheduled for surgery for tumor resection. * Ability to understand and the willingness to sign a written informed consent document. * Pathologic confirmation of a diagnosis of epithelial adenocarcinoma of the ovary, fallopian tube, or primary peritoneal cancer (serous, muc…
Location
- University of New Mexico Cancer CenterAlbuquerque, New Mexico