Characteristics and Inflammatory Markers in Children With Eosinophilic Esophagitis (EoE)
University of California, San Diego
Summary
Single center observational and specimen banking study for children with eosinophilic esophagitis EoE to gauge natural history and inflammatory markers
Description
Participants with a diagnosis of EoE are recruited from Rady Children's Hospital Eosinophilic Gastrointestinal Disorders (EGID) during routine clinic and/or endoscopy visits. Medical information including clinical symptoms, endoscopy, histopathology, medical and surgical history, lab and imaging findings, are entered into a UCSD database at each clinic or endoscopy visit. Blood and biopsy specimens are procured and utilized for analysis of inflammatory molecules and for isolation of structural cells. This protocol continues our clinical database and sample collection in children with EoE. The…
Eligibility
- Age range
- 1–65 years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * Have a known EoE diagnosis * Complain of dysphagia, vomiting, or abdominal pain, especially if recalcitrant to acid blocking therapy (but does not have to be recalcitrant to acid blocking medications) * Present with food impaction * Present with esophageal stricture * Have characteristic endoscopic findings of EoE of pallor, linear furrows, lichenification, white plaques, or concentric rings Exclusion Criteria: * None
Location
- Rady Children's Hospital San DiegoSan Diego, California