University of Delaware
Americans continue to consume high amounts of sodium. Potassium is notable for its blood pressure lowering effects but less is known regarding its effect on the vasculature. This investigation seeks to determine the role of dietary potassium on the vasculature in the presence of a high sodium diet in salt-resistant adults.
Significant public health efforts have been made towards salt reduction but most have met with failure. Dietary factors such high sodium/low potassium diets contribute to the development of cardiovascular diseases (CVDs) such as atherosclerosis and high blood pressure (BP). This is important as CVD is the number one killer in the U.S. While the role of these two nutrients on BP is widely accepted, their impact on the vasculature has received less attention. Endothelial dysfunction, characterized by impaired dilation, is an important non-traditional risk factor for atherosclerosis. Evidence sup…
Inclusion Criteria: * healthy * normal blood pressure * normal resting ECG Exclusion Criteria: * hypertension * history of heart disease * diabetes * kidney disease * obese (BMI ≥30) * significant weight changes in the last 6 months * use of tobacco products * pregnant * on a special diet (gluten free; vegan) * take any medications for the above conditions * endurance trained athletes
Consumption of 10 days of a diet moderate in potassium and low in sodium.
Consumption of 10 days of a diet moderate in potassium and high in sodium.
Consumption of 10 days of a diet high in potassium and high in sodium.
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