Optimizing Pain Control in Transurethral Resection of the Prostate
Benaroya Research Institute
Summary
The purpose of this study is to develop a multi-modal protocol for pain management after TURP that minimizes opioid use. The investigators hypothesize this approach will provide non-inferior pain control to the current standard of care which includes opioids as the primary agent. The investigators believe this is an important step in reducing the opioid epidemic in surgical patients.
Description
In our study, the investigators will randomize TURP patients to standard of care versus a multi-modal protocol. Multi-modal pain control is defined as: "analgesia that combines 2 or more agents that act by different mechanisms to provide analgesia with better pain relief and less opioids". In addition, patients in the intervention arm will receive education regarding pain control and opioid use. The investigators aim to demonstrate non-inferior pain control with this approach. The investigators hope this will inform new guidelines for pain control after TURP, minimize opioid use in this patien…
Eligibility
- Age range
- 18+ years
- Sex
- Male
- Healthy volunteers
- Yes
Inclusion Criteria: * Are identified as candidates for TURP * Are 18 years of age or greater * Are proficient in English Exclusion Criteria: * Have filled an opioid prescription in the last 2 months * Have an allergy to a medication included in the protocol * Have a history of pelvic radiation * Have renal failure (Serum Cr \> 2.0 mg/dl), peptic ulcer disease, history of gastric bypass, cirrhosis, or other contraindication precluding use of NSAID's * Have liver failure, hepatitis, or alcohol abuse which precludes use of acetaminophen
Interventions
- DrugIbuprofen 600 mg
We'll be adding ibuprofen while trying to limit oxycodone use while hospitalized. Patients will not be discharged with a narcotic.
- BehavioralEducation
We'll be adding education to patient's post-operative instructions to aid in their pain control management.
Location
- Virginia Mason Medical CenterSeattle, Washington