Transfer of Aneuploid or Mosaic Embryos Following Preimplantation Genetic Testing
Stanford University
Summary
To determine how often embryos reported to be abnormal by preimplantation genetic testing result in liveborn infants. To evaluate whether the pregnancies that result from these embryos are higher risk for complications and whether the resulting babies have higher risk for health or developmental issues in the first five years after birth.
Description
Genetic testing modality and results will be recorded Pregnancy per transfer will be recorded Patients in the study agree to provide medical records of their pregnancy. Any genetic testing or fetal testing will be carefully reviewed and recorded by the study team. For patients with live births, pediatric records will be collected for up to 5 years. As well as surveys for developmental milestones. There is no financial compensation for study participants
Eligibility
- Age range
- 18–55 years
- Sex
- Female
- Healthy volunteers
- Yes
Inclusion Criteria: * Available aneuploid or mosaic embryos * No other acceptable embryos available * Willing to travel to Stanford for treatment * English language fluency Exclusion Criteria: * Use of international donor eggs or sperm not tested according to FDA guidelines. * Living outside the United States * Embryos with Triploidy are not eligible for transfer in this protocol
Interventions
- OtherNon-euploid embryo transfer
Other than choice of embryo for transfer, all other medical interventions will be standard of care protocols
- OtherEuploid Transfer
Standard of Care Protocol
Location
- Stanford Fertility and Reproductive Medicine CenterSunnyvale, California