Feasibility of Non-Operative Management of Rectal Cancer in a Rural Population
Bassett Healthcare
Summary
This is an observational research study. Patients with rectal cancer can choose different courses of treatment. This study will follow these patients over the course of approximately six years, depending on their treatment. Patients will be monitored through clinic visits and survey assessments to see how they do, how they feel regarding their treatment choices, and their outcomes. The surveys will analyze the impact of the patients' treatment choices, as well as patient adherence, in a rural setting.
Description
Standards of care for patients with rectal cancer are evolving over time. Surgery for rectal cancer is associated with significant short- and long-term side effects for patients, including changes in bowel function, self-image, ability to work, and sexual function. Emerging data indicates that some patients experiencing complete clinical response to neoadjuvant therapy (treatment given prior to surgery) may be able to forego surgery, without compromising cancer outcomes. Current National Cancer Center Network (NCCN) guidelines for the treatment of rectal cancer states that, "...the panel belie…
Eligibility
- Age range
- 18+ years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: For a patient to be considered eligible for this study, ALL of the following conditions must be met: 1. Age 18 or greater 2. ECOG PS 0-2 3. Stage II or III, newly diagnosed, biopsy proven, rectal cancer 4. No prior treatment for rectal cancer 5. No prior pelvic radiotherapy 6. Willing to undergo study related testing and monitoring after treatment 7. Women of childbearing potential must rule out pregnancy within 2 weeks prior to registration with a blood test or urine study 8. Women must not be pregnant or breastfeeding 9. Able to provide informed consent Exclusion Crite…
Interventions
- ProcedureBowel/rectal resection
surgical removal of the portion of the rectum where the tumor was originally identified
- Othernon-operative follow up
patients who choose the non-operative option will be required to adhere to a very intensive follow up protocol, including endoscopy and CT imaging
Location
- Bassett Healthcare NetworkCooperstown, New York