Cortical-Basal Ganglia Speech Networks
Massachusetts General Hospital
Summary
In this research study the researchers want to learn more about brain activity related to speech perception and production.
Description
Speech production is disrupted in a number of neurological diseases that involve the basal ganglia, including Parkinson's disease (PD) and dystonia. The investigators will use a novel experimental approach and combination of analytic techniques to elucidate the contribution of neural activity in cortical-basal ganglia circuits to the hierarchical control of speech production, in subjects undergoing deep brain stimulation surgery.
Eligibility
- Age range
- 18–85 years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: 1. Subjects scheduled for DBS implantation, as determined by the clinical multidisciplinary movement disorders board with definitive diagnosis of Parkinson's disease, essential tremor or dystonia. 2. Subjects able to provide informed consent and comply with task instructions. 3. Subjects 18-85 years old Exclusion Criteria: 1. Subjects with reported hearing loss. 2. Non-English-speaking subjects
Interventions
- Otherelectrophysiological data collection
Electrophysiological data collection at the time of DBS surgery.
Location
- Massachusetts General HospitalBoston, Massachusetts