SEntinel Lymph Node Endometrial Cancer Trial: A Prospective Multicenter International Single-Arm Observational Trial (SELECT)
Memorial Sloan Kettering Cancer Center
Summary
This study is being done to find out how often endometrial cancer recurs after the standard treatment as well as how often the standard treatment results in a lymphedema.
Eligibility
- Age range
- 18+ years
- Sex
- Female
- Healthy volunteers
- No
Screening Inclusion Criteria: * ECOG performance status 0-1 or KPS ≥ 70% * Age ≥ 18 years * Endometrioid adenocarcinoma histologic diagnosis on endometrial biopsy or dilatation and curettage * No evidence of extrauterine disease, or suspicious pelvic lymph nodes, or distant metastases, or cervical invasion on pre-operative conventional imaging studies (Pelvic +/- Abdomen CT or MRI or sonogram, or body PET scan) and physical examination (uterine confined by exam and imaging ) * Suitable candidate for surgery * Planned surgical treatment including hysterectomy in combination with SLN biopsy and…
Interventions
- OtherPhysical exam
Part 2 participants will be prospectively followed clinically for relapse for 30 months from the date of surgery for physical examination at post-ops visits.
Locations (19)
- Hartford Healthcare Cancer Institute @ Hartford HospitalHartford, Connecticut
- University of Miami (Data Collection Only)Miami, Florida
- Miami Cancer Institute Baptist Health South FloridaMiami, Florida
- ADVENTHEALTH (Data collection only)Orlando, Florida
- Mayo Clinic (Data Collection and Data Analysis)Rochester, Minnesota
- Memorial Sloan Kettering Basking Ridge (All protocol activities)Basking Ridge, New Jersey