University of Alabama at Birmingham
This study seeks to examine the effects of a heterozygous mutation of the AGXT gene in a stone forming population on endogenous oxalate production. Participants will consume a controlled low-oxalate diet and provide blood and urine samples to measure the amount of oxalate in their bodies.
Inclusion Criteria: * at least 18 years of age * history of calcium oxalate stones * heterozygous mutation of the AGXT gene, as evidenced by results from the Invitae Nephrolithiasis Panel * willingness to comply with a controlled diet for five days Exclusion Criteria: * pregnant individuals * individuals who are currently breast feeding
Participants will consume a controlled low oxalate diet for five days.
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