A Prospective Study of a Mosaic Embryo Transfer
Colorado Center for Reproductive Medicine
Summary
This research is a prospective study in which the purpose is to investigate the clinical outcomes following the transfer of a mosaic embryo (presence of both chromosomally normal and abnormal cells) that has been screened for preimplantation genetic testing (PGT).
Description
This research is a prospective study with the purpose is to investigate the clinical outcomes following the transfer of a mosaic embryo (presence of both chromosomally normal and abnormal cells) that has been screened for preimplantation genetic testing (PGT). PGT involves the biopsy and testing of a handful (3-6) of trophectoderm (pre-placental cells) from the embryo. Embryos that are screened as mosaic via PGT, as a standard, are not offered for transfer for pregnancy attempt. Publications have shown that mosaic embryos and mosaic fetuses can result in healthy live births (Wallerstein et al,…
Eligibility
- Age range
- 18–45 years
- Sex
- Female
- Healthy volunteers
- Yes
Inclusion Criteria: * Women age 18-45 Infertile women who have completed an IVF cycle with PGT at the Colorado Center for Reproductive Medicine (CCRM) that have a mosaic embryo * Patients can be of any race, culture, sexual orientation or ethnicity * Patients that are willing to transfer a single embryo Exclusion Criteria: * Patients that do not meet the clinical requirements for an embryo transfer per clinic standards. * Patients that desire more than a single embryo transfer. * Patients that are using a gestational carrier. * Embryonic mosaic PGT results that include chromosome errors 13,…
Interventions
- ProcedureTransfer of mosaic embryo
Subjects will transfer a mosaic embryo transferred to their uterus
Location
- Colorado Center for Reproductive MedicineLone Tree, Colorado