Analysis of the Tumor Microenvironment and Immune Response in Malignant Melanoma
Ohio State University Comprehensive Cancer Center
Summary
This study collects and stores blood and tumor samples from patients with malignant melanoma and healthy individuals. The purpose of this study is to gain a better understanding of the causes of melanoma and how melanoma tumors behave. Storing blood and tumor samples for future research may lead to new discoveries that may ultimately help with diagnosing or treating this disease.
Description
PRIMARY OBJECTIVE: I. Facilitate studies aimed at investigating new prognostic markers and potentially therapeutic therapies in malignant melanoma. OUTLINE: Patients undergo collection of blood samples at the time of the initial diagnostic work-up, and possibly prior to the initiation of surgery, chemotherapy, immunotherapy, or radiation therapy, at tumor progression or recurrence, and annually during routine follow-up (no more than 4 blood draws per year). Patients may also undergo collection of tissue sample during standard of care surgical or radiologic procedures. Healthy individuals un…
Eligibility
- Age range
- Not specified
- Sex
- All
- Healthy volunteers
- Yes
Inclusion Criteria: * Patient with malignant melanoma or personal history of melanoma * Normal donors * Informed consent can be obtained * Patients with any stage of malignant melanoma Exclusion Criteria: * Incarcerated individuals will be excluded from this protocol
Interventions
- ProcedureBiospecimen Collection
Undergo collection of blood and tissue samples
Location
- Ohio State University Comprehensive Cancer CenterColumbus, Ohio