Use of an Intrauterine Manipulator and Its Correlation with Positive Peritoneal Cytology in Early Stage Endometrial Cancers
WellSpan Health
Summary
This study aims to answer whether use of a Vcare® intrauterine manipulator leads to an increased incidence of positive peritoneal cytology in patients undergoing surgical management of early stage (FIGO stage I/II) endometrial cancer.
Description
Endometrial cancer is the sixth most common cancer diagnosed in women worldwide and the leading gynecologic cancer in developed countries, accounting for nearly 50% of all newly diagnosed gynecologic cancers in the United States . The majority of endometrial cancers are diagnosed at an early stage which portends a favorable prognosis. Despite early diagnosis and generally favorable prognosis in these cancers, approximately 13% of patients will experience recurrence . Most recurrences occur in patients with known high-risk pathologic features, however approximately 3% of recurrences occur in pa…
Eligibility
- Age range
- 18+ years
- Sex
- Female
- Healthy volunteers
- No
Inclusion Criteria: * Subjects age 18 or older able to give informed consent * Biopsy diagnosed endometrial cancer (including endometrioid, serous, mucinous and clear cell histologies) * Planned standard of care surgical management of early stage endometrial cancer * No clinical evidence of disseminated intraperitoneal disease Exclusion Criteria: * Final pathology does not reflect diagnosis of endometrial cancer (including endometrioid, serous, mucinous, and clear cell histology) * Evidence of disseminated intraperitoneal disease * Subject is not a surgical candidate * Subject elects for fe…
Interventions
- Proceduresurgical staging
Patients will undergo standard surgical staging for endometrial cancer utilizing either a V-care uterine manipulator or sponge stick
Location
- Wellspan HealthYork, Pennsylvania