Natural History of Post-Coronavirus Disease 19 Convalescence at the National Institutes of Health
National Institute of Neurological Disorders and Stroke (NINDS)
Summary
Background: People who get COVID-19 have a wide range of symptoms. They also recover from COVID-19 in different ways. In this study, researchers will use survey data to describe the different ways people experience and recover from COVID-19. They will also use the data to help create future studies to understand why some people do not fully recover. Objective: To learn more about the range and timing of symptoms that people have before, during, and after COVID-19 infection. Eligibility: People ages 18 and older who can give documentation of a positive COVID-19 or antibody test. Design: Participants will be screened with a telephone interview. It will take 15 minutes. They will provide their COVID-19 test results and medical records. Participants will complete a second telephone interview. It will take 30 60 minutes. They will also take online surveys every 3 months for 3 years. The interview and surveys will ask participants about their health before they got COVID-19, what happened while they had COVID-19, and what their recovery has been like. Participants will get log-in data to take the online surveys. Completing all of the surveys the first time may take up to 3 hours. Follow-up surveys will take up to 30 minutes. Participants do not have to complete the surveys in one sitting. They will be able to save their progress and finish the surveys later. Participants may be contacted to take part in other research studies.
Description
Study Description: In late 2019, the novel coronavirus SARS/CoV2 appeared in Wuhan, China. The various ways that humans will recover from COVID-19 is just starting to be observed and it is clear there will be a wide range of convalescent experiences. A year into the pandemic, the post-acute sequelae of SARS/CoV2 infection (PASC) is known to be common and includes a broad range of symptoms and potential pathologies. This phased protocol is designed to observe and study the convalescence and recoveries from acute SARS/CoV2 infections. Phase A Phase A Surveying (Phase A) will enable people in t…
Eligibility
- Age range
- 18–100 years
- Sex
- All
- Healthy volunteers
- No
* INCLUSION CRITERIA: For Phase A Surveying: 1590 persons who are recovering or have recovered from an acute SARS/CoV2 infection will participate. Inclusion criteria for Phase A: Post-COVID-19 Convalescence (n=890) 1. Participants 18 and older 2. Ability to provide informed consent 3. Stated willingness to complete telephone interviews 4 Reports having begun recovery from an acute SARS/CoV2 infection in the past 5 years a.For participants who don t have a known recovery date, a date of 6 weeks from infection will be imposed 5 Provides documentation of a positive COVID-19 Test. Approved…
Location
- National Institutes of Health Clinical CenterBethesda, Maryland