Children's Protein Requirements With Physical Activity: The ChiPP Study
Arkansas Children's Hospital Research Institute
Summary
There is reason to believe the current dietary reference intakes for dietary protein for children are too low. Furthermore, children with high levels of physical activity and fitness may require a higher requirement. To better understand the protein requirements in minimally and highly physically fit and active children 8-10 y old, investigators will use the indicator amino acid oxidation technique.
Description
Purpose: Determine dietary protein requirements using the indicator amino acid oxidation (IAAO) method in a group of thoroughly phenotyped school-age children who engage in different levels of Physical Activity. Hypothesis: Daily dietary protein requirements are greater in children with high level of physical activity vs. sedentary children. Justification: Adequate dietary protein intake is essential to support cellular integrity, physical growth and function. Although dietary protein malnutrition is not prevalent in the U.S., highly active individuals may require greater than the average pr…
Eligibility
- Age range
- 8–10 years
- Sex
- All
- Healthy volunteers
- Yes
Inclusion Criteria: * Inclusion Criteria * Boys or girls * Ages 8-10 years * All races * All ethnicities * Children who were determined to have normal weight (BMI \<85th percentile) already determined under Mitochondria (MI) Energy (IRB Protocol: 260376) * Participants willing to stop taking nutritional supplements (e.g., multivitamins, vitamin D, fish oil, probiotics, prebiotics, immune boosters, and others) for at least 2 weeks prior to each study testing visit * Children without an infection requiring antibiotics willing to be rescheduled after at least 2 months of finalizin…
Interventions
- Dietary SupplementDietary Supplement: Dietary supplement: Protein intake
Oral consumption of hourly experimental meals. Includes 4 meals containing a mixture of free amino acids, carbohydrates and fats from a protein-free formula mixture. The last 4 meals will contain labelled 13C phenylalanine.
Location
- Arkansas Children's Nutrition CenterLittle Rock, Arkansas