Application of Lung Ultrasound Artefact Analysis for Exclusion of Acute Rejection in Asymptomatic Lung Transplant Recipients
Mayo Clinic
Summary
This study is being done to study a safe and non-invasive way to diagnose lung rejection and infection.
Description
Lung transplant recipients are at high risk for lung rejection and lung infection after transplant. This is diagnosed by performing lung bronchoscopies and lung biopsies. These procedures carry an increased risk for complications and are costly. This study is being done to study a safe and non-invasive way to diagnose lung rejection and infection.
Eligibility
- Age range
- 18+ years
- Sex
- All
- Healthy volunteers
- Yes
Inclusion Criteria: * Adult patients (\> 18 yrs) who had undergone single/double/heart-lung transplant * Asymptomatic * Normal spirometry defined as a FEV1 without significant drop from baseline (significant drop = \>10% decrease from baseline) * Clear chest radiograph over allograft Exclusion Criteria: * Patients who are unable to consent for the procedure * Patients with subcutaneous emphysema or other technical challenges that could interfere with satisfactory image acquisition- as deemed by the operator.
Interventions
- Diagnostic TestLung ultrasound
The lung ultrasound will be performed by a trained pulmonologist by gently pressing a probe to various areas of your chest. This is a non-invasive procedure and you should not feel any pain. The ultrasound will take less than 10 minutes.
Location
- Mayo Clinic in FloridaJacksonville, Florida