Bio-Banking of Specimens for Advanced Lung Disease and Lung Transplant Research
Baylor Research Institute
Summary
A major goal of this protocol is to support biomarker studies in advanced lung diseases, lung transplantation care, and to improve our understanding of the effects of viral and other infectious exposures to outcomes in our lung transplant and ALD patient populations.
Description
The identification of biomarkers in a patient's blood or tissue that are specific for particular medical conditions (such as interstitial lung disease, chronic obstructive lung disease (COPD), and post-lung transplant rejection) is important for the prevention and early detection of the disease, as well as to advance our understanding of targeted therapies. Availability of biomarkers for diagnosis and for the prediction of patient prognosis and therapy promises personalized medicine. Patients may be selected based on the presence of particular gene mutations or circulating protein levels to re…
Eligibility
- Age range
- 18+ years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: 1. All individuals aged 18 years and older 2. Persons who have undergone lung transplantation at Baylor University Medical Center in the previous 10 years 3. Individual is able to understand and sign the informed consent form Exclusion Criteria: 1. Significant documented anemia (hemoglobin \<8 g/dL) 2. Blood transfusions within past 3 weeks 3. Active cancer (non-skin cancers) 4. Enrollment against doctor recommendation 5. Patient not able to provide informed consent
Interventions
- OtherPatient Biospecimen Registry (observational and blood sampling)
Clinical data collected at every blood sample collection visit.
Location
- Baylor Scott & White Research InstituteDallas, Texas