Ohio State University
The primary objective of this study is to determine whether the effect of continuous positive airway pressure (CPAP) therapy on 24-hour mean blood pressure (BP) in patients with obstructive sleep apnea (OSA) varies between symptom phenotypes.
This is a prospective, non-randomized, multi-center, cohort study involving patients with moderate to severe OSA. This study will compare OSA patients who accept and comply with CPAP therapy versus those who do not. Variables of Interest: 24-hour ambulatory BP, sitting BP, electrocardiogram (ECG), facial photographs, psychomotor vigilance test (PVT), questionnaires, and blood samples. Patients will complete questionnaires that pertain to demographics, lifestyle factors, and co-morbidities associated with CVD. The blood samples will be used to look for evidence of diabetes; elevated lipids; m…
Inclusion Criteria: * 30 to 75 years of age * Among patients with hypertension, no change in BP medication for at least 3 months. * Willing and able to give informed consent * Willing and able to complete ambulatory blood pressure monitoring at baseline and after 6-months. * Sleep study \[Polysomnography (PSG) or Home Sleep Apnea Study (HSAT) performed based on clinical grounds * 4% oxygen desaturation index (ODI4) ≥15 events/hour on clinical sleep study * Planned CPAP treatment by treating provider Exclusion Criteria: * Unable to apply BP cuff (e.g. arm circumference \>55 cm, prior breast…
CPAP treatment of obstructive sleep apnea.
Arctuva estimate
Verify or correct the compensation shown for this listing.