Personalized Responses to Dietary Composition Trial 3
Zoe Global Limited
Summary
The PREDICT 3 study will build on previous research in over 2,000 individuals to further refine machine learning models that predict individual responses to foods, with the aim of advancing precision nutrition science and individualized dietary advice. The study incorporates both standardized and controlled dietary intervention, for the purpose of testing postprandial responses to specific mixed meals, in addition to a free-living period with a dietary record for measuring responses to a large variety of meals consumed in a realistic context, where the role of external factors (e.g. exercise, sleep, time of day) on postprandial responses may be determined. For the first time this PREDICT study is built on top of a commercial product which will allow access to a much larger group of participants who are already collecting large amounts of data through digital and biochemical devices that can contribute to science.
Description
Choice of design: The study is a single arm mechanistic intervention study. Study population: The subject must have enrolled in the commercial ZOE testing program in order to apply for participation in the PREDICT 3 research program. Screening Assessment: The study eligibility criteria listed below closely match to the commercial eligibility criteria, which ZOE users consent to before enrolling in the commercial program. Study duration: Each participant will take part in the study for 6-14 days. Dietary intervention: The dietary intervention will be carried out on up to 6 days with the opt…
Eligibility
- Age range
- 18+ years
- Sex
- All
- Healthy volunteers
- Yes
Inclusion Criteria: * Enrolled in the commercial ZOE testing program * Any sex * Minimum 18 years of age (minimum 19 years of age in Alabama and Nebraska due to state laws) * Body mass index (BMI) of greater than or equal to 16.5 kg/m2. * Living in the continental US states, other than in New York (excluded from the ZOE testing product also as they are unable to access the dried blood spot service provided by Quest), or living in the UK * Able and willing to comply with the study protocol and provide informed consent. * Under care for chronic medical conditions (including eating disorders, ty…
Interventions
- OtherDietary Intervention
To carry out a dietary intervention using standardized test meals, where the participant's postprandial response to the meal is measured and is used to predict their postprandial responses to other foods, along with input variables including metabolic profile, anthropometry, sleep and exercise.
Locations (2)
- Zoe US Inc.Needham, Massachusetts
- King's College LondonLondon