An Evaluator-blinded Randomized Controlled Trial Study of the Effect of Anti-inflammatory Diet in Subjects With Rheumatoid Arthritis.
University of California, San Diego
Summary
In a previous exploratory study, the investigators observed an effect on disease activity outcomes of anti-inflammatory diet. The investigators also observed change in microbiome and circulating metabolites. The current study will determine whether or not the addition of anti-inflammatory diet improves the clinical outcomes in participants with rheumatoid arthritis, and the role of microbiome and circulating metabolites.
Eligibility
- Age range
- 18+ years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * Patients with low or moderate disease activity (defined as Clinical Disease Activity Index ≤ 22) and without changes in disease activity or therapy during the previous 3 months, who are interested in dietary intervention, and are able to provide consent and attend to follow up visits. Exclusion Criteria: * Pregnancy or lactating. Patients that will become pregnant during the study will be remove from the study. * Food allergies * Subjects with significant other comorbidities and /or medication use which in physician's clinical judgment might difficult the interpretatio…
Interventions
- OtherDiet 1
Dietary intervention
- OtherDiet 2
Dietary intervention
Location
- UCSDLa Jolla, California