Sleep Duration and Cardiovascular Health
Oregon Health and Science University
Summary
This is a cross-sectional study with an optional intervention that will examine how extreme sleep durations relate to cardiovascular health, physical activity, and sleep quality by studying three groups of participants: short sleepers (≤ 6 hrs), long sleepers (≥ 9 hrs), and average duration sleepers (7-8 hrs). The optional intervention asks participants to maintain an 8-hour per night regular sleep schedule for one week.
Description
PRIMARY OBJECTIVES: 1\. To test the hypothesis that vascular endothelial function in the brachial artery, and other associated cardiovascular risk markers are impaired in short sleepers and long sleepers as compared to the control group of average duration sleepers. To test the hypothesis that the optional intervention to maintain an 8-hour per night sleep schedule will alleviate vascular endothelial function impairment. OUTLINE: Participants will measure sleep, physical activity, and blood pressure with at-home devices before coming in for one in-lab visit, where they will have vascular f…
Eligibility
- Age range
- 25–65 years
- Sex
- All
- Healthy volunteers
- Yes
Inclusion Criteria: * Men and women ages 25-65y * Lean and overweight (BMI 18.5-40 kg/m2) * No acute, chronic, or debilitating medical conditions * No prescription/non-prescription medications or drugs of abuse * Current non-smoker (tobacco and marijuana) * Persons who fit all the above criteria and are suitable based on a medical history and health habits questionnaire, and additional sleep and health profiling questionnaires may be eligible to participate. Exclusion Criteria: * Persons with any acute, chronic, or debilitating medical condition except pre-hypertension will be excluded. * P…
Interventions
- BehavioralRegularized Sleep Schedule
Participants may maintain a self-selected 8-hour per night sleep schedule as an optional intervention. Participants from any of the three groups may complete the intervention.
Location
- Oregon Health and Science UniversityPortland, Oregon