Incisional Hernia Prevention After Open Hepatectomy by Small Tissue Bite Fascial Closure: A Randomized Clinical Trial
M.D. Anderson Cancer Center
Summary
This clinical trial compares two different kinds of surgical closing techniques, short stitch suture or traditional suture, in patients who are having liver tumor surgery. This study may help researchers learn if one technique can lower the chances of developing a hole in the wall of the abdomen (an abdominal hernia) at the incision site better than the other.
Description
PRIMARY OBJECTIVE: I. To assess whether small bites abdominal wall closure reduces the risk of developing incisional hernia following liver surgery. SECONDARY OBJECTIVES: I. To compare short-term perioperative outcomes between small bites and typical fascial closure technique. II. To assess the hernia incidence rate of short stich versus (vs.) standard closure in subgroups of patients with inverted-L or midline incisions. III. To assess the hernia incidence rate of Kawaguchi-Gayet hepatectomy complexity classifications I/II vs. III (hernia rate by extent of hepatectomy). IV. To assess th…
Eligibility
- Age range
- 18+ years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * Patients undergoing hepatectomy for malignant diagnosis (primary or secondary) from 5/1/2021 through 11/1/2024 will be eligible for inclusion in this study * Elective surgery * Age \>= 18 * Planned midline laparotomy incision or inverted-L incision Exclusion Criteria: * Pre-existing abdominal hernia * History of mesh placement at prior laparotomy * Pregnant women
Interventions
- OtherQuality-of-Life Assessment
Ancillary studies
- ProcedureSurgical Procedure
Undergo hepatectomy using small bites fascial method for abdominal wall closure
- ProcedureSurgical Procedure
Undergo hepatectomy using conventional fascial method for abdominal wall closure
Location
- M D Anderson Cancer CenterHouston, Texas