Exercise Time of Day for Cardiometabolic Health in Type 2 Diabetes
Rutgers, The State University of New Jersey
Summary
The overall purpose of the study is to test the effect of Noom on exercise and diet advice in adults with type 2 diabetes. The overarching hypothesis is that the use of Noom may promote better dietary adherence during an exercise program, thereby promoting greater weight loss and cardiometabolic health compared to lifestyle advice only. In particular, the investigators anticipate that changes in metabolic and vascular insulin sensitivity will correlate with glycemic control and blood pressure changes.
Description
Type 2 diabetes (T2D) is associated with a 3-fold cardiovascular disease (CVD) mortality risk compared with healthy controls, and it is estimated that 30 million adults in the United States have the disease. In recent years the American Diabetes Association (ADA) and American College of Sports Medicine (ACSM) recommend moderate intensity (40-60% heart rate max, HRmax) aerobic exercise 3-5d/wk for the management of T2D. The statement also recognized that higher exercise intensity (\>60% HRmax) predicts better blood glucose control than exercise volume. Cardiovascular health (e.g. fitness, blood…
Eligibility
- Age range
- 30–70 years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * Male or female \>30 and \<70 years old. * Has a body mass index \>28 and \<45 kg/m2. * Previously diagnosed with T2DM. * Subjects currently taking medications that affect heart rate and rhythm (i.e. Ca++ channel blockers, nitrates, alpha- or beta-blockers). Exclusion Criteria: * Morbidly obese patients (BMI \>46 kg/m2) and overweight/lean patients (BMI \<27 kg/m2) * Evidence of type 1 diabetes and diabetics requiring insulin therapy * Subjects who have not been weight stable (\>2 kg weight change in past 3 months) * Subjects who have been recently active (\>30 min of m…
Interventions
- BehavioralMorning Exercise
Exercise at moderate to hard intensity will be performed in the morning for up to 10 sessions for about 1 hour under supervision in the morning.
- BehavioralAfternoon Exercise
Exercise at moderate to hard intensity will be performed in the morning for up to 10 sessions for about 1 hour under supervision in the afternoon.
Locations (3)
- New Jersey Institute for Food, Nutrition, and HealthNew Brunswick, New Jersey
- Robert Wood Johnson University Hospital Clinical Research CenterNew Brunswick, New Jersey
- Rutgers University Loree GymnasiumNew Brunswick, New Jersey