Ultrasound Vibroelastography in Post-Prostatectomy Erectile Dysfunction
Mayo Clinic
Summary
Researchers are trying to determine whether there is additional utility to using vibroelastography, a noninvasive ultrasound technique to evaluate for the presence of tissue fibrosis, in conjunction with standard penile duplex Doppler ultrasound to assess erectile function (recovery) after prostate cancer surgery.
Eligibility
- Age range
- 40+ years
- Sex
- Male
- Healthy volunteers
- No
Inclusion criteria include: * Age \> 40 years * Clinically localized prostate cancer (American Urological Association Grade Groups 1-2; cT1c or cT2a-b; PSA \< 10) without clinic or imaging evidence of localized extra-prostatic or metastatic disease (i.e. AUA low and favorable intermediate risk prostate cancer) * International Index of Erectile Function (IIEF) of ≥ 21 points at baseline (no or mild erectile dysfunction) * Patient-expressed interest in consultation for sexual function (erectile function) preservation/ optimization * Planned bilateral nerves-paring prostatectomy Exclusion crite…
Interventions
- Diagnostic TestUlrasound Vibroelastography (UVE)
Ultrasound technique to quantitatively assess tissue stiffness (elasticity and viscosity) by applying vibration through a specialized probe (indenter).
Location
- Mayo Clinic in RochesterRochester, Minnesota