Washington University School of Medicine
This project capitalizes on a natural experiment imposed by the COVID-19 pandemic in conjunction with an extensive set of cognitive, emotional, biological, and neuroimaging variables already collected at multiple time points in older adults participating in a clinical trial of exercise and mindfulness. This project will elucidate the effects of stress on cognitive function and emotional health in later life, including biological measures of Alzheimer Disease risk, stress, and aging, with the ultimate goal of discovering how to mitigate these effects, among older adults who have made and maintained a lifestyle change.
Inclusion Criteria: * Participated in the parent study, Protocol ID #201410093 Exclusion Criteria: * Inability to safely continue classes or complete assessments, as per PI discretion
Mindfulness-Based Stress Reduction
Exercise
Mindfulness-Based Stress Reduction + Exercise
Health Education
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