Improving Colonoscopy Adenoma Detection Metrics by Extending the Screening-only Measurement to All Indications: a Prospective Multicenter Study
Evergreen General Hospital, Taiwan
Summary
This is a prospective equivalence colonoscopy study evaluating whether overall adenoma detection rate (ADR) is a reliable alternate for screening ADR. Overall indication includes screening, surveillance, and diagnostic indications.
Description
This multicenter study will be conducted by 18 colonoscopists from 5 hospitals in Taiwan, including Evergreen general hospital, E-da hospital, E-da Dachang hospital, Linkou Chang Gung memorial hospital, and Keelung Chang Gung memorial hospital, and plans to recruit 2700 prospective participants in a 2-year period. Felix W. Leung from Sepulveda Ambulatory Care Center, Veterans Affairs Greater Los Angeles Healthcare System (USA) will be involved in the study design, and will participate in data analyses and report preparation. Consecutive patients aged ≥50 years undergoing colonoscopy are eligib…
Eligibility
- Age range
- 50–80 years
- Sex
- All
- Healthy volunteers
- Not specified
Inclusion Criteria: * consecutive patients aged ≥50 years undergoing colonoscopy are eligible for enrollment. Exclusion Criteria: * high risk family history of colorectal cancer (CRC) e.g., familial adenomatous polyposis, hereditary non-polyposis CRC syndrome, multiple first degree relatives with CRC, or a single first degree relative with CRC at \<60 years * serrated polyposis syndrome * inflammatory bowel disease * colonoscopy to remove a large neoplastic polyps * obstructive lesions of the colon * gastrointestinal bleeding * current participation in other studies * hospitalized patients…
Interventions
- OtherComparison of ADR
The investigators will compare ADRs using traditional screening-restricted definition and combined screening, surveillance, and diagnostic indication (i.e., overall-non-FIT indication). The impact of addition of FIT+ indication into the overall indication (i.e., overall-FIT indication) on ADR will also be evaluated.
Locations (6)
- Sepulveda Ambulatory Care Center, VAGLAHSNorth Hills, California
- E-Da Dachang HospitalKaohsiung City
- E-Da HospitalKaohsiung City
- Keelung Chang Gung Memorial HospitalKeelung
- Evergreen General HospitalTaoyuan
- Linkou Chang Gung Memorial HospitalTaoyuan