Effect of Acute Nitrate Supplementation on Vascular Function in Hispanic, Black and White Population
University of Texas at Austin
Summary
The purpose of the study is to assess vascular function in African Americans, Hispanic and Caucasian Americans to better understand racial differences in cardiovascular health. The investigators will further investigate the affect of Beetroot juice on the vascular function of all participants.
Description
African Americans and Hispanic individuals have the highest incidence of type 2 diabetes, which increases their risk of all cardiovascular diseases. One of the hallmarks of type 2 diabetes is vascular dysfunction, caused by a lack of nitric oxide bioavailability. Vascular function and blood flow responses to exercise have been shown to improve after nitrate supplementation (beetroot juice), However, whether nitrate supplementation will improve vascular function in African American and Hispanic individuals remains unknown. The investigators will perform a randomized, placebo-controlled study in…
Eligibility
- Age range
- 18–65 years
- Sex
- All
- Healthy volunteers
- Yes
Inclusion Criteria: * Healthy men and women who are either Caucasian American, Hispanic, or non-Hispanic African American Exclusion Criteria: * Blood pressure higher than or equal to 140/90 mmHg * BMI \> 35kg/m2 * Have a history of cardiovascular, neurological or vascular diseases * Take prescription medications * Are smokers * Are pregnant
Interventions
- Dietary SupplementBeetroot juice
high nitrate supplement
- Dietary SupplementPlacebo drink
placebo
Location
- University of Texas at AustinAustin, Texas