Trans-Pacific Multicenter Collaborative Study of Minimally Invasive Proximal Versus Total Gastrectomy for Proximal Gastric and Gastroesophageal Junction Cancers
M.D. Anderson Cancer Center
Summary
To compare the symptoms of patients who have a MIPG to the symptoms of patients who have a MITG.
Description
Primary Objective: Delineate the short-term appetite of patients who undergo minimally-invasive proximal gastrectomy (MIPG) and compare them with those of patients with gastric and gastroesophageal adenocarcinoma who undergo total gastrectomy (MITG). We hypothesize that MIPG is associated with better postoperative appetite levels compared to MITG, which would result in improved nutritional status and maintained body weight after surgery. Secondary Objective: \- Assess patient-reported outcomes (PROs) and nutrition measures. We will use the MD Anderson Symptom Inventory Gastrointestinal Canc…
Eligibility
- Age range
- 18+ years
- Sex
- All
- Healthy volunteers
- No
Inclusion: 1. Able to speak and read English, Spanish, Japanese or Korean 2. Participants with a biopsy-confirmed diagnosis of non-metastatic gastric or GEJ adenocarcinoma, who are scheduled to undergo MIPG or MITG for curative-intention 3. Age ≥ 18 Exclusion: 1. Participants with known malabsorption syndromes or a lack of physical integrity of the upper gastrointestinal tract 2. Participants with known narcotic dependence, with average daily dose \> 5 mg oral morphine equivalent 3. Participants deemed unable to comply with study and/or follow-up procedures, at investigators' discretion 4.…
Interventions
- OtherStandard of Care
complete a questionnaire within 30 days before your surgery and then at 1, 3, 6, and 12 months after surgery
- OtherControl Group
complete a questionnaire within 30 days before your surgery and then at 1, 3, 6, and 12 months after surgery
Locations (4)
- Mayo Clinic in RochesterRochester, Minnesota
- M D Anderson Cancer CenterHouston, Texas
- Keio University School of MedicineTokyo
- Yonsei University College of MedicineSoeul