South Asians and Coronary Plaque Registry
University of Texas Southwestern Medical Center
Summary
Individuals who self-report as SAs will be recruited to participate in this registry as well as non-SA controls for comparison. All individuals who consent to participate will 1) complete a survey assessing demographics, medical history, family medical history; 2) have blood collection; 3) and CCTA assessment. These data will be combined with clinical data from the electronic health record and, if applicable, the Dallas Hearts and Mind Study and other research studies, for research purposes. The registry will serve to generate primary observations as well as preliminary data for future studies.
Description
To establish a registry of individuals who self-report as South Asian ethnicity with coronary plaque assessment to better understand plaque characteristics in this high-risk group and facilitate future studies investigating the increased coronary disease risk in this population. South Asian individuals (SAs) are an expanding minority group in the United States (U.S.) with marked excess cardio-metabolic risk. SAs (primarily India, Pakistan, Bangladesh, Nepal, Sri Lanka) are one of the fastest-growing minority groups in the U.S., with an estimated 40% population growth from 2010-2017 (5.4 milli…
Eligibility
- Age range
- 18+ years
- Sex
- All
- Healthy volunteers
- Yes
Inclusion Criteria: * Males and Females: Age 18 years or above * South Asian (SA) adults through self-identification (South Asians to have both biological parents with ancestry from India, Pakistan, Sri Lanka, Nepal and Bangladesh) * We also propose to enroll an equivalent number of individuals of other descent as a comparator group (Non SA Adult Volunteers) * Sampling Method: Probability Sample Exclusion Criteria: * Under the age of 18 years * Unable to give informed consent * Impaired renal function: estimated glomerular filtration rate ≤ 45ml/min * Baseline heart rate≥70 bpm or ≥66 bpm a…
Interventions
- Diagnostic TestCoronary CT Angiogram
A computerized tomography (CT) coronary angiogram is non-invasive imaging test that looks at the arteries that supply blood to your heart.
Location
- University of Texas Southwestern Medical CenterDallas, Texas