Intracardiac Flow Assessment in Cardiac Amyloidosis
Mayo Clinic
Summary
The primary objective of this study is to define the intracardiac flow imaging biomarkers in cardiac amyloidosis.
Eligibility
- Age range
- 40+ years
- Sex
- All
- Healthy volunteers
- Yes
Inclusion Criteria: * Subject is clinically stable without cardio-vascular-related hospitalizations within 6 weeks prior to enrollment as assessed by the investigators. * Subject is able to provide written informed consent and is willing and able to complete study procedures. * Currently in sinus rhythm by clinical assessment or documented electrocardiographic studies. * Subject and disease characteristics noted by medical record review: * Healthy control volunteers must also meet the following criteria: Karnofsky performance scale \> 80%; ECOG status 0 or 1. * ATTR cardiac amyloidosis b…
Interventions
- Diagnostic TestCardiac magnetic resonance image (CMR)
A magnetic resonance imaging study for assessment of cardiac structure and intracardiac flow
- Diagnostic TestTransthoracic Echocardiogram (TTE)
An imaging test that uses soundwaves that cannot be heard (ultrasound) to take pictures of the heart and vessels.
- Diagnostic TestSix-minute Walk Test
A self-paced, test of exercise capacity performed unencouraged intensity that measures the distance that patients can walk on a flat, hard surface in a period of 6 minutes
Location
- Mayo ClinicRochester, Minnesota