An Exercise and COgnitive Rehabilitation Intervention for Older Cancer Survivors (The E-Co Study)
University of Rochester
Summary
The objective of the study is to evaluate the feasibility of a combined mobile health exercise and cognitive rehabilitation intervention and its effect on cognition in a single-arm pilot study that recruits cancer survivors.
Description
Cancer survivors (i.e., those who completed cancer-directed treatment) often experience long-term treatment-related effects, such as cancer-related cognitive decline (CRCD). Exercise and cognitive rehabilitation (rehab) interventions have been shown to improve CRCD symptoms in both cancer and non-cancer populations. Among older adults without cancer, studies have also demonstrated that multicomponent interventions combining exercise and cognitive rehab are more effective in improving cognitive dysfunction than either intervention alone. However, exercise adherence and self-efficacy are lower i…
Eligibility
- Age range
- 60+ years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * Age ≥60 years at the time of consent * Have a diagnosis of any cancer * Have completed curative intent treatments * Patients on endocrine therapies are allowed to enroll * Patients with hematologic malignancies after autologous or allogeneic stem cell transplant are allowed to enroll as long as they have completed curative-intent treatment * Have concerns about memory or other thinking abilities following cancer treatment\* * English speaking (because the interventions are available in English language only) * Eastern Cooperative Oncology Group (ECOG) performance st…
Interventions
- BehavioralE-Co
The E-Co intervention will integrate active components of a mobile health exercise intervention (GO-EXCAP) into a cognitive rehabilitation intervention (MAAT-G).
Location
- University of RochesterRochester, New York