Structural Priming as a Treatment Component in Aphasia
Purdue University
Summary
This project focuses on developing a novel treatment for sentence production and comprehension in aphasia, using implicit priming. First set of experiments will aim examine which learning conditions are most effective in creating maximal training gains. Then, in a later study, the investigators will develop and test the efficacy of a novel treatment study based on findings from the first set of the studies.
Description
Over five years, the investigators will conduct a series of studies to develop a novel intervention strategy for improving sentence production and comprehension in persons with aphasia. Specifically, the investigators will use implicit learning of grammar as a novel facilitator for language recovery in aphasia. The planned studies seek to test the hypothesis that implicit learning alters the central language system in PWA, creating lasting and generalized improvements in both sentence production and comprehension. Aim 1 will determine the extent to which different learning conditions modulate…
Eligibility
- Age range
- 21–85 years
- Sex
- All
- Healthy volunteers
- Yes
Inclusion Criteria: * Individuals with post-stroke aphasia * At least 6 months post-onset of eft hemisphere stroke * Native speaker of English * Normal or corrected to normal hearing and vision * High-school educated * Difficulty communicating in sentences, with some ability to use words independently Exclusion Criteria: * Severe apraxia of speech * Other neurological conditions affecting communication (e.g., dementia) * Uncontrolled psychiatric/psychological conditions affecting thinking and communication * Active alcohol/substance abuse
Interventions
- BehavioralSentence training
Participants will be trained to read, make, and recall sentences during each session.
Location
- Purdue UniversityWest Lafayette, Indiana