Neuroimmune Mechanisms Underlying Electroacupuncture Effect on Vascular Function
University of California, Irvine
Summary
Acupuncture therapy will be provided to reduce blood pressure in hypertensive patients. The mild to moderate hypertensive patients will be either on or off hypertensive medications. The course last for 8 weeks and the frequency is once a week.
Description
Improvement in BP control rates would lead to one of the largest impacts in improving life expectancy and the quality of life for over 100 million people in the United States and 1 billion people worldwide with immediate and measurable results. In the United States, 80% of patients with HTN are treated, but BP is controlled in only half of these individuals, with control worsening with increasing age. The reasons for inadequate treatment and BP control are complex, but one reason for this therapeutic misalignment may be an incomplete understanding of the mechanisms underlying the development a…
Eligibility
- Age range
- 45–75 years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: 1. Subjects from 45 to 75 years of age 2. Clinically diagnosed with mild to moderate hypertension and ON or OFF medication (Office SBP \> 140 mmHg and \< 160 mmHg Or ABPM average SBP \> 130 mmHg and \< 145 mmHg), and 3. No significant ECG change reflecting ischemia (i.e. ST elevation or depression) at rest will be recruited to participate in this study. Exclusion Criteria: 1. Subjects will be excluded if pregnant or nursing. 2. Subjects will be excluded if they have coronary disease (by history or on ECG screening), conduction abnormalities on ECG consistent with left bu…
Interventions
- Otherelectroacupuncture
acupuncture needling and stimulation are applied for 30 min
Locations (2)
- Susan Samueli Integrative Health InstituteIrvine, California
- University of California, Irvine, Health Sciences Medical CenterOrange, California