Network Effects of Therapeutic Deep Brain Stimulation
The University of Texas Health Science Center, Houston
Summary
The purpose of this study is to map the acute, short-term cortical evoked responses to thalamic electrical stimulation in persons with intractable epilepsy
Eligibility
- Age range
- 18+ years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * diagnosis of Epilepsy * undergoing neuromodulation therapy with clinically implanted neuromodulation devices (DBS, RNS) * followed in the outpatient epilepsy clinic Exclusion Criteria: * pregnant women * active psychosis, major depression, or suicidal ideation in the preceding year * Intelligence quotient (IQ) less than 70 as measured by clinical neuropsychological evaluation * Do not agree to share their medical records for research purposes
Interventions
- DeviceRNS/DBS activation
This will be performed to study the EEG responses to DBS/RNS stimulation electrical pulses. The stimulation frequencies will be sequentially increased and each stimulation will last for 2 minutes.There will be a 1-2 minute wash out period after each trial.
Location
- The University of Texas Health Science Center at HoustonHouston, Texas