Non-weight Bearing Exercise for Accelerated Healing of Diabetic Foot Ulcers
University of Michigan
Summary
The goal of this study is to improve the therapeutic management of diabetic foot ulcers (DFU). The main questions to answer are if a program of non-weight bearing exercise helps the DFU heal faster than standard wound care. This randomized clinical trial will determine how blood flow to the ulcer and whole body metabolism may be improved with exercise. Participants will be randomized to either exercise + standard wound care or standard wound care alone and undergo testing for leg blood flow, fitness and measures of metabolism through blood draws. The intervention period is 6-weeks. Eligible participants must have an existing foot ulcer uncomplicated by infection and be medically cleared to exercise.
Description
This research is being done because people with diabetes have reduced healing capacity. This can be problematic because wounds that do not heal may turn into ulcers which may lead to more severe complications. Non-weight bearing exercise has many positive health benefits that improve metabolic and vascular health which will then improve healing time. Therefore, the purpose of this study is to evaluate the positive effects of non-weight bearing exercise. Once the effects of non-weight bearing exercise are confirmed, progress towards the prevention and treatment of diabetic foot ulcers and compl…
Eligibility
- Age range
- 18–75 years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: 1. Provision of signed and dated informed consent 2. Stated willingness to comply with all study procedures and availability for the duration of the study 3. Male or Female, aged 18 yrs or older 4. Diabetes diagnosed or meets ADA criteria for Type 2 diabetes 5. Foot ulcer of diabetic etiology, with all of the following characteristics: * Ulcer size \> 0.5cm2 and \< 12cm2 at least 2 cm from any other ulcer * Ulcer with Wagner grade 1 or 2 6. In case of multiple ulcers, select the largest ulcer that meets inclusion criteria. Exclusion Criteria: 1. Patient participat…
Interventions
- Behavioralnon-weight bearing exercise
exercise on a non-weight bearing device at 50% of peak capacity, 3 days per week for 6 weeks
Location
- School of KinesiologyAnn Arbor, Michigan