University of Chicago
The purpose of this study is to determine whether or not Magnetic Resonance Images (MRI) will identify high-grade cancers earlier and more frequently in men at high risk of developing prostate cancer.
In this study the study team hypothesizes MR images will identify high-grade cancers earlier and more frequently in men at high risk of developing prostate cancer. Subjects will receive gadolinium (intravenous contrast agent) as part of their research MRI exam. While the deposition of gadolinium (Gd) has been demonstrated in numerous studies, the clinical consequences of Gd deposition are unknown. Gd enhanced MRI scans provide crucial medical information regarding prostate and prostate cancer imaging and contrast-enhanced images are a component of all guidelines and the PIRADS scoring system.…
Inclusion Criteria: * Male age 18 and older * No known history of prostate cancer * No previous prostate resection or ablation (e.g. TURP, photovaporization) Exclusion Criteria: * Unable to tolerate MRI due to metal fragments or claustrophobia * Lack of a rectum * Hip arthroplasty
Group placement is determined by GRS score, Family history, and germline testing
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