Utility of Oral Dexmedetomidine as the Sole Sedative Agent in Pediatric Population Undergoing MRI
Soroush Merchant
Summary
The objective of this preliminary study is to assess the utility of oral dexmedetomidine as the sole sedative agent in pediatric population undergoing MRI.
Description
MRI is an important and robust medical imaging technique that has become the cornerstone for radiologic studies. Superior image quality and resolution especially for soft tissue imaging, without the use of ionizing radiation, has made MRI a dominant imaging modality in pediatrics. Despite its many advantages, MRI is not child friendly. Lengthy scan times, the need for lying motionless in a confined space, excessive noise and vibration during image acquisition, are all factors that have made anesthesia an integral part of pediatric MRI. General anesthesia is a state of medically induced uncons…
Eligibility
- Age range
- 3–6 years
- Sex
- All
- Healthy volunteers
- Yes
Inclusion Criteria: 1. Participants 3-6 years old, male and female, all races and ethnicities 2. Requiring a clinically indicated MRI with general anesthesia Exclusion Criteria: 1. Refusal to take oral dexmedetomidine 2. Known allergy to dexmedetomidine 3. Inability to take dexmedetomidine at least 90 minutes prior to start of the MRI 4. Medical contraindications to administration of dexmedetomidine including: 1. Unstable cardiac status including life threatening arrhythmias, abnormal cardiac anatomy, significant cardiac dysfunction 2. Current use of digoxin 3. Moya Moya disease…
Interventions
- DrugDexmedetomidine
Participants will receive oral dexmedetomidine as the sole sedative agent for undergoing MRI
- DrugGeneral Anesthesia (control group)
Participants will receive general anesthesia for their MRI
Location
- Children's Mercy HospitalKansas City, Missouri