Pulse Oximetry Accuracy by Skin Color
Brittany Willer
Summary
This is a prospective, non-randomized, non-blinded comparative study to evaluate the accuracy of pulse oximetry compared to co-oximetry in dark-skinned (Black) compared to lighter-skinned (White) children undergoing anesthesia, using standard FDA performance statistics as measured by mean bias and accuracy root mean squared to evaluate device performance.
Description
This is a prospective, non-randomized, non-blinded comparative study. There will be no changes to the anesthetic or surgical plan to accommodate this study. Patients undergoing anesthesia will be induced per their anesthetic team. Following endotracheal intubation, the patient will be placed on air (FiO2 21%) at 4 liters per minute fresh gas flow. After a minimum of 3 minutes has elapsed, the anesthesia team will obtain an arterial blood sample of approximately 1 mL. This can be obtained from an arterial line if one is planned for the procedure or already in place by accessing the line per st…
Eligibility
- Age range
- 2–9 years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * Children aged 2-9 years undergoing general anesthesia with or without arterial line placement. Exclusion Criteria: * Patients with cyanotic congenital heart disease. * Patients with bleeding disorders. * Patients taking blood thinners.
Interventions
- Diagnostic TestArterial blood gas with co-oximetry
1 mL blood sample for ABG-CoOx analysis to obtain co-oximetry measured arterial oxygen saturation (SaO2C) and standard ABG derived arterial oxygen saturation (SaO2S).
Location
- Nationwide Children's HospitalColumbus, Ohio