Variable Intensive Early Walking Post-Stroke -2 (VIEWS-2)
Indiana University
Summary
The proposed research will evaluate the individual and combined effects of task-specificity and intensity of rehabilitation interventions on locomotor function, community mobility and quality of life in patients with subacute (1-6 months) post-stroke.
Description
The objective of this Phase II clinical trial is to identify how exercise training parameters, particularly the specificity and intensity of stepping practice, influence long-term mobility outcomes in patients with subacute stroke. Previous work indicates these variables can influence the efficacy of training interventions in individuals without neurological injury, with some data to support their utility in chronic stroke. However, studies that systematically assess the independent and combined effects of these principles in individuals early following stroke are sparse. This critical researc…
Eligibility
- Age range
- 18–85 years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * Sub-acute stroke (1-6 months) * Hemiparesis (Fugl-Meyer \<34) without cerebellar deficits * Ability to ambulate with or without physical assistance over 10 meters but \< 1.0 m/s and assistive devices and below-knee bracing is allowed. * Ability to sit \> 30 seconds without upper-extremity support or physical assistance * Ability to follow 3-step commands * Provision of informed consent and medical clearance from a supervising physician or medical provider to participate * Must have the ability to consent or have a legal health care power of attorney or legally authorized…
Interventions
- BehavioralHigh-intensity, task-specific (i.e., walking) interventions
Up to 30 1-hr sessions of training focused on walking trying to achieve higher cardiovascular intensities
- BehavioralHigh-intensity, non-specific physical therapy interventions
Up to 30 1-hr sessions of training focused on varied physical interventions trying to achieve higher cardiovascular intensities
- BehavioralLow-intensity, task-specific physical therapy interventions
Up to 30 1-hr sessions of training focused on walking trying to achieve lower cardiovascular intensities
- BehavioralLow-intensity, non-specific physical therapy interventions
Up to 30 1-hr sessions of training focused on varied physical interventions trying to achieve lower cardiovascular intensities
Location
- Rehabilitation Hospital of IndianaIndianapolis, Indiana