University of Pennsylvania
The aims of this project, called "Surveillance of Healthcare-associated infections \& Antimicrobial Resistance", or "SHARE", are to 1) enhance laboratory capacity to detect emerging AMR patterns; 2) strengthen hospital epidemiology programs to use data to prevent, detect, and contain emerging AMR threats; 3) deploy study teams to answer critical public health surveillance questions, and 4) to build a national network of infection prevention and control (IPC) resources to prevent, detect, and contain emerging infectious disease threats
The World Health Organization (WHO) has declared antimicrobial resistance (AMR) one of the top 10 global public health threats facing humanity. AMR burden is higher in low-and-middle-income countries (LMICs) where, in recent decades, incidence and mortality from healthcare-associated infections (HAI) due to multidrug resistant organisms (MDRO) have dramatically increased. For example, neonatal sepsis is the third most common cause of neonatal deaths and multidrug-resistant Gram-negative bacteria are now the leading cause of sepsis among hospitalized neonates in south Asia and sub-Saharan Afric…
Inclusion Criteria: * hospital inpatient admission to participating wards. Exclusion Criteria: * diagnosis of a bleeding disorder * platelet counts of \<50,000 * diagnosis of coagulopathy * presence of active bleeding * inability to have a nares swab collected due to some other condition where nasal swabbing would be contraindicated * inability to have a rectal swab collected due to some other condition where rectal swabbing would be contraindicated
routine part of hospital IPC activities
Arctuva estimate
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