Dual Energy CT Decreased IV Contrast Dose Imaging for TAVR
University of Maryland, Baltimore
Summary
A standard polyenergetic CT (computed tomography) procedure utilizes 100 ml of iodinated contrast. A recent world-wide shortage of iodine based intravenous contrast has highlighted the need to search for alternative methods or doses. Reducing iodinated IV contrast dose can mitigate IV contrast supply shortages and enable significant cost savings for the radiology practice and hospital system. In addition, decreased IV contrast dose can potentially reduce the rate of acute kidney injury, specifically in patients with decreased renal function. The purpose of the study is to determine whether low IV contrast dose CT with monoenergetic reconstruction can be use for presurgical planning of transcatheter valve replacement (TAVR) procedure.
Eligibility
- Age range
- 18–88 years
- Sex
- All
- Healthy volunteers
- Yes
Inclusion Criteria: * scheduled to receive TAVR abdominal CT Exclusion Criteria: * cannot undergo CT scan * Allergy to intravenous contrast not controlled by steroids or benadryl * GFR\<30
Interventions
- Combination ProductIodinated Contrast Agent (Omnipaque)
Standard dosage of Omnipaque for CT imaging is 100 ml. Cohort will be given a reduced dosage.
- DeviceDual Energy CT
Dual energy CT scanners enable monoenergetic CT image reconstruction which allows for improved iodine image contrast.
Location
- University of Maryland Medical CenterBaltimore, Maryland