Massachusetts General Hospital
The overall goal of this study is to develop OCT Vibrography (aka OCT elastography) as a novel tool for measuring biomechanical properties of human tissues in vivo.
The overall goal of this study is to develop OCT Vibrography (aka OCT elastography) as a novel tool for measuring biomechanical properties of human tissues in vivo. The investigators aim to establish baseline data in healthy subjects, compare elastic moduli in different tissue types, and measure differences in elastic moduli between keratoconus and normal eyes. If successful, this project will provide useful, previously inaccessible elastic parameters and advance the investigators' understanding of the relationship between the bulk mechanical properties and the microstructure of the human tiss…
Group 1: Inclusion criteria: • Subjects with healthy eyes (age 18 - 75, N = 50) Exclusion criteria: * Subjects with history of eye diseases, and previous eye surgeries. * Subjects with diabetes, glaucoma family history * Subjects allergic to anesthetic eyedrop, especially proparacaine * Subjects with severe allergy * Subjects who have difficulty biting * Subjects who have recurrent corneal erosion Group 2: Inclusion criteria: • Subjects with healthy skin (age 18 - 75, N = 10) Exclusion criteria: • Subjects with open cuts/sores on the skin, skin infection, or any contagious skin condit…
OCT vibrography
Arctuva estimate
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