Opioid-Sparing Effects of Nurse-Delivered Hypnosis During Breast Cancer Surgery
M.D. Anderson Cancer Center
Summary
To hypnosedation alone given before and during surgery on reducing opioid use after surgery compared to standard general anesthesia given alone or with hypnosedation.
Description
OBJECTIVES The proposed trial will randomize women and men with stage 0/I breast cancer scheduled for a lumpectomy, including excisional biopsy, ± sentinel node biopsy to one of three groups: 1) surgery with a local anesthetic, fentanyl, and HS before and during surgery (HS); 2) HS before surgery with usual care general anesthesia (HS-GA; total intravenous anesthesia rendering the patient unconscious with propofol infusion, airway instrumentation with a laryngeal mask airway or endotracheal tube, fentanyl, and local anesthetic); or 3) Usual care general anesthesia same as HS-GA group (GA). Th…
Eligibility
- Age range
- 18+ years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: 1. Men and Women; 2. Age 18 or older; 3. Scheduled for a unilateral, breast surgical procedure, ± SLND 4. Able to read, write and speak English or Spanish 5. Able to sign a written informed consent and be willing to follow protocol requirements Exclusion Criteria: 1. Extreme mobility issues that preclude participating in the study 2. Major thought disorders such as schizophrenia or uncontrolled bipolar disorder or PTSD 3. History of chronic opioid use 4. Current pain 2 or above on 0-10 scale 5. Co-mobilities such as uncontrollable diabetes or hypertension 6. Plastic surg…
Interventions
- BehavioralGroup 1
Participants will receive hypnosedation will be restarted after arriving in the operating room and will continue for the whole time of surgery
- BehavioralGroup 2
Participants will receive standard general anesthesia and medications to control your pain after arriving in the operating room
- BehavioralGroup 3
Participants will receive standard general anesthesia and medications during surgery to control your pain.
Location
- M D Anderson Cancer CenterHouston, Texas