Surface-Knit and Reformulate CADENCE-Kids for Translation: The SKyRoCKeT Study
University of North Carolina, Charlotte
Summary
The SKyRoCKeT Study (Surface-Knit and Reformulate CADENCE-Kids for Translation) will recruit a sex- and age-balanced sample of 360 young people 6-20 years of age to develop an integrative, physiologically-coherent age-cadence-log(metabolic equivalent, MET) surface-based model, reformulate the prior R21 CADENCE-Kids study (1; NCT01989104) by providing individualized, more precise, age-specific and coherent cadence-intensity thresholds, investigate additional differences by anthropometric factors, and translate cadence-intensity thresholds to over-ground walking. The SKyRoCKeT Study is an innovative critical step to provide a coherent, interpretable, objectively monitored step-based intensity metric to inform (inter)national physical activity (PA) guidelines by transforming currently vague guidelines of PA intensity into quantifiable PA recommendations that can be of widespread use, which clinicians, young people, parents, and researchers can integrate into preventive care management and action plans for personalized care. The SKyRoCKeT Study will allow for a user-friendly, interpretable metric to more accurately inform public health/behavioral interventions, assessments, analyses, school-based health and physical education curricula and programs, and public health messages for young people and their caregivers.
Description
Specific Aims: The SKyRoCKeT Study will: 1. Expand CADENCE-Kids (1; NCT01989104) to innovatively surface-'knit' the age dimension through a continuous, unbiased-by-age, and physiologically-coherent age-cadence-log(MET) flexible surface approach without artificially-generated jumps between age ranges and with enhanced precision of cadence-intensity threshold estimates. This single surface will coherently transition between ages, borrow inter-age information, and be data-driven. 2. Reformulate CADENCE-Kids (1; NCT01989104) by providing age-specific cadence-intensity thresholds, calculated with…
Eligibility
- Age range
- 6–20 years
- Sex
- All
- Healthy volunteers
- Yes
Inclusion Criteria: * Between 6 - 20 years of age on the day of signing the informed consent/assent. * Able to walk without the need of assistance Exclusion Criteria: * Need for assistance with walking including the use of a wheelchair * Mental illness requiring hospitalization within the past 5 years * Medical condition or medications that affect(s) changes in heart rate with exercise * Current pregnancy * Pacemaker or other implanted medical device including metal joint replacements * History of cardiovascular disease, stroke, transient ischemic attacks (TIA, mini-stroke), chest pain, unu…
Interventions
- OtherN/A: SKyRoCKeT is an observational study
None; this is an observational study
Location
- University of North Carolina at CharlotteCharlotte, North Carolina